Description

(S)-2-(4-tert-Butyl-4,5-Dihydrooxazol-2-Yl)Propan-2-Ol is a high-value, chiral oxazoline derivative used as a critical building block in asymmetric synthesis. This compound matters for its role as a versatile ligand precursor and chiral auxiliary, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to control stereochemistry in complex synthetic routes.

Application

• As a chiral ligand precursor in asymmetric catalysis, including hydrogenation and carbon-carbon bond-forming reactions.
• As a key chiral auxiliary in the stereoselective synthesis of active pharmaceutical ingredients (APIs).
• In the research and development of novel agrochemicals requiring specific stereochemistry for biological activity.
• For the preparation of advanced materials where molecular chirality influences macroscopic properties.
• As a standard or reference compound in analytical method development for chiral separation techniques (e.g., chiral HPLC).
• In academic and industrial research focused on developing new methodologies in organic and organometallic chemistry.

Basic Information

Product Name	(S)-2-(4-tert-Butyl-4,5-Dihydrooxazol-2-Yl)Propan-2-Ol
CAS No.	204333-19-7
Molecular Formula	C₁₀H₁₉NO₂
Molecular Weight	185.26 g/mol
Synonyms	(S)-2-(4-tert-Butyl-4,5-dihydrooxazol-2-yl)propan-2-ol; (S)-2-(4-tert-Butyl-2-oxazolin-2-yl)-2-propanol; (S)-tert-Butyl Oxazoline Propanol; (S)-4-tert-Butyl-2-(2-hydroxy-2-propyl)-4,5-dihydrooxazole; (S)-HBTM; (S)-2-(4-tert-Butyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-ol; Chiral Oxazoline Alcohol; 204333-19-7
EINECS	Contact for details

Quality Control

Our (S)-2-(4-tert-Butyl-4,5-Dihydrooxazol-2-Yl)Propan-2-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.