Description

2-Bromo-2-(2-Fluorophenyl)-1-Cyclopropylethanone is a specialized fluorinated and brominated ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a reactive α-bromo ketone moiety with a cyclopropyl ring and a fluorinated aromatic system, enabling precise structural modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of complex molecules, particularly in medicinal chemistry programs targeting novel bioactive entities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, especially those requiring fluorinated and cyclopropane-containing scaffolds.
• Agrochemical Research: Used in developing novel active ingredients for crop protection, leveraging the bioisosteric properties of fluorine.
• Chemical Biology Probes: Serves as a precursor for labeling reagents or probe molecules to study biological mechanisms.
• Material Science: Potential building block for specialty polymers or advanced organic materials with tailored properties.
• Academic & Contract Research: Employed in methodological studies and custom synthesis projects exploring new reaction pathways.

Basic Information

Product Name	2-Bromo-2-(2-Fluorophenyl)-1-Cyclopropylethanone
CAS No.	204205-33-4
Molecular Formula	C₁₁H₁₀BrFO
Molecular Weight	257.10 g/mol
Synonyms	2-Bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone; α-Bromo-2-fluorophenyl cyclopropyl ketone; 1-Cyclopropyl-2-(2-fluorophenyl)-2-bromoethanone; 2-(2-Fluorophenyl)-2-bromo-1-cyclopropylethanone; (2-Bromo-2-(2-fluorophenyl)acetyl)cyclopropane; Cyclopropyl 2-bromo-2-(2-fluorophenyl) ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-2-(2-Fluorophenyl)-1-Cyclopropylethanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.