Description

1,1,1-Trifluoro-2-Cyano-2-Butanol is a versatile fluorinated building block characterized by its trifluoromethyl and cyano functional groups. This compound is highly valued in advanced organic synthesis for introducing fluorine atoms and nitrile handles, which are critical for modulating the physicochemical properties of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of fluorinated drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides with enhanced metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique surface properties and chemical resistance.
• Fluorinated Surfactant & Coating Additives: Building block for surface-active agents and coating materials requiring low surface energy.
• Chemical Research & Development: A valuable reagent for methodology development in fluorination and cyano chemistry.

Basic Information

Product Name	1,1,1-Trifluoro-2-Cyano-2-Butanol
CAS No.	203302-91-4
Molecular Formula	C5H6F3NO
Molecular Weight	153.10 g/mol
Synonyms	2-Cyano-1,1,1-trifluoro-2-butanol; 1,1,1-Trifluoro-2-hydroxy-2-methylbutyronitrile; 2-Butanol, 1,1,1-trifluoro-2-cyano-; α-Hydroxy-α-methyl-γ,γ,γ-trifluorobutyronitrile; 2-Methyl-2-hydroxy-4,4,4-trifluorobutyronitrile; TF-CB; Trifluoromethyl cyano alcohol intermediate
EINECS	Contact for details

Quality Control

Every batch of 1,1,1-Trifluoro-2-Cyano-2-Butanol is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and reliable performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.