Description

1-Bromo-2-Methyl-4,4,4-Trifluorobutane is a specialized fluorinated organic bromide building block, valued for its unique combination of a reactive bromine handle and a trifluoromethyl group. This compound is critical for introducing fluorinated alkyl chains into target molecules, significantly altering their physicochemical properties. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring enhanced lipophilicity, metabolic stability, or specific electronic characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) containing trifluoromethyl motifs, which are prevalent in modern drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF3 group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fluorinated precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorine into polymer backbones or side chains to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A versatile alkylating agent in nucleophilic substitution reactions for constructing complex fluorinated organic molecules in R&D laboratories.
• Refrigerant & Propellant Research: Investigated as a potential component or precursor in next-generation fluorinated working fluids with lower global warming potential.

Basic Information

Product Name	1-Bromo-2-Methyl-4,4,4-Trifluorobutane
CAS No.	203302-90-3
Molecular Formula	C5H8BrF3
Molecular Weight	205.02 g/mol
Synonyms	2-Methyl-4,4,4-trifluorobutyl bromide; 4,4,4-Trifluoro-2-methyl-1-bromobutane; 1-Bromo-2-methyl-4,4,4-trifluorobutane; 2-Methyl-1-bromo-4,4,4-trifluorobutane; Butane, 1-bromo-2-methyl-4,4,4-trifluoro-; (2-Methyl-4,4,4-trifluorobutyl)bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Methyl-4,4,4-Trifluorobutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.55 g/cm³
Refractive Index (n20/D)	~1.40

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.