Description

2,4-Dibromo-6-Fluoroiodobenzene is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and iodine substituents, makes it a versatile precursor for constructing complex molecules via selective cross-coupling and functional group transformations. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Used in the synthesis of organic electronic materials, liquid crystals, and advanced polymers where halogenated aromatic cores are required.
• Cross-Coupling Reactions: The iodine and bromine atoms provide orthogonal reactivity for sequential Suzuki, Stille, or Sonogashira coupling reactions to build complex biaryl systems.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2,4-Dibromo-6-Fluoroiodobenzene
CAS No.	202982-76-1
Molecular Formula	C6H2Br2FI
Molecular Weight	403.79 g/mol
Synonyms	1,3-Dibromo-5-fluoro-2-iodobenzene; Benzene, 2,4-dibromo-1-fluoro-3-iodo-; 2,4-Dibromo-1-fluoro-3-iodobenzene; 3-Iodo-2,4-dibromo-1-fluorobenzene; 2,4-Dibromo-6-fluoro-1-iodobenzene; 6-Fluoro-2,4-dibromo-1-iodobenzene
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-6-Fluoroiodobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to minimize decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.