Description

3-Fluoro-5-(Trifluoromethyl)Phenacyl Bromide is a versatile and highly functionalized organic bromide intermediate. Its value lies in the strategic combination of fluorine atoms and a reactive phenacyl bromide group, making it a critical building block for synthesizing complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with enhanced activity and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic cores used in electronic display technologies.
• Functional Polymer Monomer: Enables the introduction of fluorine and reactive sites into polymer chains for specialty coatings and high-performance resins.
• Cross-Coupling Reactions: Acts as an electrophile in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and creating custom chemical libraries.

Basic Information

Item	Details
Product Name	3-Fluoro-5-(Trifluoromethyl)Phenacyl Bromide
CAS No.	202664-38-8
Molecular Formula	C9H5BrF4O
Molecular Weight	285.04 g/mol
Synonyms	2-Bromo-1-[3-fluoro-5-(trifluoromethyl)phenyl]ethan-1-one; 3-Fluoro-5-(trifluoromethyl)phenacyl bromide; 2-Bromo-3'-fluoro-5'-(trifluoromethyl)acetophenone; α-Bromo-3-fluoro-5-(trifluoromethyl)acetophenone; 1-(3-Fluoro-5-(trifluoromethyl)phenyl)-2-bromoethanone; Bromo(3-fluoro-5-(trifluoromethyl)phenyl)methanone; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-(Trifluoromethyl)Phenacyl Bromide is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.