Description

3-Ethyl-4-(Hydroxymethyl)Benzonitrile is a versatile benzonitrile derivative featuring both an ethyl and a hydroxymethyl substituent on the aromatic ring. This unique structure makes it a valuable building block and key intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and functional materials. It is primarily sought after by research and development teams and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the nitrile and hydroxymethyl functional groups for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating advanced organic electronic compounds used in displays and lighting technologies.
• Polymer Modifier: The hydroxymethyl group allows for incorporation into polymer chains to modify thermal or mechanical properties.
• Fine Chemical Synthesis: Employed in multi-step organic reactions to construct complex molecules for research and small-scale commercial production.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki or Heck couplings to form biaryl structures.

Basic Information

Product Name	3-Ethyl-4-(Hydroxymethyl)Benzonitrile
CAS No.	202522-03-0
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	4-(Hydroxymethyl)-3-ethylbenzonitrile; 3-Ethyl-4-(hydroxymethyl)benzonitrile; 3-Ethyl-4-cyanobenzyl alcohol; 4-Cyano-2-ethylbenzyl alcohol; 2-Ethyl-4-cyanobenzyl alcohol; Benzonitrile, 3-ethyl-4-(hydroxymethyl)-; (3-Ethyl-4-cyanophenyl)methanol
EINECS	Contact for details

Quality Control

Our 3-Ethyl-4-(Hydroxymethyl)Benzonitrile is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.