Description

Methyl 4-Amino-3-Chloro-5-Methylbenzoate is a high-purity, multi-functional benzoate derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both amino and chloro substituents, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical and agrochemical sectors, where precise chemical functionality is paramount for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting specific biological pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Dye and Pigment Manufacturing: Serves as a foundational component for creating specialized azo dyes and high-performance organic pigments.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymeric materials.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl structures.
• Custom Synthesis and Contract Manufacturing: A versatile starting material for custom synthesis projects in fine chemical and R&D laboratories.

Basic Information

Product Name	Methyl 4-Amino-3-Chloro-5-Methylbenzoate
CAS No.	202146-16-5
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	Methyl 4-Amino-3-Chloro-5-Methylbenzoate; Benzoic acid, 4-amino-3-chloro-5-methyl-, methyl ester; 4-Amino-3-chloro-5-methylbenzoic acid methyl ester; Methyl 4-amino-3-chloro-5-methylbenzoate; 3-Chloro-4-amino-5-methylbenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Amino-3-Chloro-5-Methylbenzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We operate under a cGMP-compliant quality system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.