Description

4-Amino-3-Bromo-5-Chlorobenzonitrile is a high-purity, multi-functional halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for constructing complex molecular architectures with precision. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in OLED device fabrication.
• Dye and Pigment Industry: Utilized in the synthesis of advanced colorants and photographic chemicals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions due to the bromo and amino substituents.

Basic Information

Item	Detail
Product Name	4-Amino-3-Bromo-5-Chlorobenzonitrile
CAS No.	201857-39-8
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	3-Bromo-5-chloro-4-aminobenzonitrile; 4-Amino-3-bromo-5-chlorobenzene carbonitrile; 2-Bromo-6-chloro-3-cyanobenzenamine; 3-Cyano-2-bromo-6-chloroaniline; Benzonitrile, 4-amino-3-bromo-5-chloro-; 201857-39-8; 4-Amino-3-bromo-5-chloro-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Bromo-5-Chlorobenzonitrile is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification parameters are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.