Description

Bis(Neopentyl Glycolato)Diboron is a high-purity, crystalline organoboron compound widely used as a versatile reagent in advanced organic synthesis. This compound matters for its exceptional utility as a boron source in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel compounds and fine chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron source for coupling with aryl/vinyl halides to form biaryl and styrenyl structures, crucial in pharmaceutical intermediate synthesis.
• Pharmaceutical Intermediate Synthesis: Used in the preparation of active pharmaceutical ingredients (APIs) and complex drug candidates requiring precise boron incorporation.
• Agrochemical Research & Development: Employed in creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Advanced Material Precursors: Serves as a building block for boron-containing polymers, liquid crystals, and organic electronic materials.
• Catalyst & Ligand Development: Utilized in the synthesis of novel boron-based catalysts and supporting ligands for transition metal catalysis.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and process optimization studies.

Basic Information

Product Name	Bis(Neopentyl Glycolato)Diboron
CAS No.	201733-56-4
Molecular Formula	C12H24B2O4
Molecular Weight	253.94 g/mol
Synonyms	Bis(neopentyl glycolato)diboron; Diboron Neopentyl Glycolate; Neopentyl Glycol Diboron Ester; B2(neopentyl glycolato)2; B2(neo-pin)2; Bis(pinacolato)diboron Analog; 2,2-Dimethylpropane-1,3-diol diboron ester; (4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)boronic Acid Neopentyl Ester (related structure)
EINECS	Contact for details

Quality Control

Our Bis(Neopentyl Glycolato)Diboron is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR (¹¹B, ¹H, ¹³C), HPLC, and Karl Fischer titration, to confirm identity, purity, and moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Isolate from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
¹¹B NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.