Description

Boc-Hci-Oh CAS NO 201418-83-9 is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis and pharmaceutical research. Its primary value lies in providing a robust protective group for the amino functionality, enabling selective reactions during the construction of complex peptide chains. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and development.

Application

• Peptide Synthesis: Serves as a key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) and therapeutic peptides.
• Bioconjugation: Acts as a reagent for modifying biomolecules, enabling the creation of peptide-protein conjugates.
• Organic Synthesis: Functions as a versatile building block for constructing more complex organic molecules and heterocycles.
• Proteomics Research: Employed in the study of protein structure, function, and interactions.
• Combinatorial Chemistry: Utilized in the generation of diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	Boc-Hci-Oh
CAS No.	201418-83-9
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	Boc-Hci-OH; (2S,4R)-1-[(tert-Butoxy)carbonyl]-4-hydroxyproline; Boc-4-Hyp-OH; Boc-trans-4-Hydroxy-L-proline; Boc-Hydroxyproline; tert-Butoxycarbonyl-4-hydroxy-L-proline; N-Boc-4-hydroxy-L-proline; (2S,4R)-4-Hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Boc-Hci-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and cGMP applications. Quality is verified through comprehensive analytical testing including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation [α]D20	-75.0° to -80.0° (c=1, AcOH)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.