Description

Cyclopropanecarboxylic Acid, 2-[(Acetyloxy)Methyl]-, (1R-Trans)- (9Ci) is a high-purity, chiral cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate the unique structural and stereochemical properties of the cyclopropane ring into complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of potential drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a precursor for developing novel pesticides and herbicides that leverage the biological activity of cyclopropane-containing compounds.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new chiral catalysts and studies of stereoselective reactions.
• Fine Chemical Production: Serves as a building block for synthesizing complex fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.
• Material Science Research: Investigated as a monomer or modifier for creating polymers with unique thermal or mechanical properties derived from the strained cyclopropane ring.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-[(Acetyloxy)Methyl]-, (1R-Trans)- (9Ci)
CAS No.	201337-81-7
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(1R,2S)-2-(Acetoxymethyl)cyclopropanecarboxylic Acid; (1R-trans)-2-[(Acetyloxy)methyl]cyclopropanecarboxylic Acid; trans-(1R,2S)-2-(Acetoxymethyl)cyclopropanecarboxylic Acid; (1R,2S)-Rel-2-[(Acetyloxy)methyl]cyclopropanecarboxylic Acid; (-)-trans-2-(Acetoxymethyl)cyclopropanecarboxylic Acid; Chiral Cyclopropane Acetoxy Acid Ester; (1R,2S)-2-Carboxycyclopropylmethyl Acetate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-[(Acetyloxy)Methyl]-, (1R-Trans)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.