Description

Cyclopropanecarboxaldehyde, 1-Ethenyl-2-(Thioxomethyl)-, (1R,2S)-Rel- (9Ci) is a specialized chiral building block featuring a cyclopropane ring, an aldehyde, and a thioxomethyl functional group. This compound is valued for its unique stereochemistry and reactive sites, making it a critical intermediate in advanced organic synthesis. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex, biologically active molecules. The CAS number for this compound is 201046-22-2.

Application

This chiral synthon is designed for high-value synthetic applications where precise stereocontrol is paramount.

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging the biological activity imparted by the cyclopropane and sulfur-containing motifs.
• Asymmetric Catalysis & Ligand Synthesis: Employed in the preparation of chiral ligands and catalysts for enantioselective transformations.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	Cyclopropanecarboxaldehyde, 1-Ethenyl-2-(Thioxomethyl)-, (1R,2S)-Rel- (9Ci)
CAS No.	201046-22-2
Molecular Formula	C7H8OS
Molecular Weight	140.20 g/mol
Synonyms	(1R,2S)-rel-1-Ethenyl-2-(thioxomethyl)cyclopropanecarboxaldehyde; rel-(1R,2S)-1-Vinyl-2-(thioxomethyl)cyclopropanecarbaldehyde; 1-Vinyl-2-(thioxomethyl)cyclopropanecarboxaldehyde (rel-(1R,2S)-); (1R,2S)-1-Vinyl-2-(mercaptomethyl)cyclopropanecarbaldehyde (tautomer); Cyclopropanecarboxaldehyde, 1-ethenyl-2-(thioxomethyl)-, (1R,2S)-rel-; CAS 201046-22-2
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarboxaldehyde, 1-Ethenyl-2-(Thioxomethyl)-, (1R,2S)-Rel- (9Ci) is produced and analyzed under strict quality management protocols. We ensure high chiral purity and chemical integrity through advanced analytical techniques including chiral HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. This material is easily oxidized; prolonged exposure to air or elevated temperatures should be avoided. The storage area should be cool, dry, and well-ventilated.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.