Description

2-Bromo-4-Nitro-1-(Trifluoromethoxy)Benzene is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromo, nitro, and trifluoromethoxy substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated or fluorinated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the nitro and trifluoromethoxy groups contribute to biological activity.
• Material Science Research: Serves as a building block for advanced organic materials, such as liquid crystals, organic semiconductors, and polymers with specific optical or electronic properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form biaryl structures.
• Functional Dye & Pigment Intermediate: Employed in the synthesis of complex dyes and pigments where the electron-withdrawing groups influence color and stability.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial laboratories.

Basic Information

Product Name	2-Bromo-4-Nitro-1-(Trifluoromethoxy)Benzene
CAS No.	200958-40-3
Molecular Formula	C7H3BrF3NO3
Molecular Weight	285.99 g/mol
Synonyms	1-Bromo-2-nitro-4-(trifluoromethoxy)benzene; 2-Bromo-4-nitro-1-(trifluoromethoxy)benzene; 2-Bromo-4-nitro-alpha,alpha,α-trifluoroanisole; 2-Bromo-4-nitro(trifluoromethoxy)benzene; Benzene, 2-bromo-4-nitro-1-(trifluoromethoxy)-; 2-Nitro-4-bromo-1-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Nitro-1-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality assurance and supply reliability supports critical R&D and scale-up processes for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.