Description

Polyketomycin CAS NO 200625-47-4 is a complex polyketide antibiotic derived from microbial fermentation. This compound is of significant interest in pharmaceutical research and development due to its potent biological activity against a range of Gram-positive bacteria. It serves as a critical building block and reference standard for researchers in the fields of antibiotic discovery, medicinal chemistry, and biochemistry. Industries focused on developing novel anti-infective agents and studying bacterial resistance mechanisms are the primary users of this high-purity biochemical.

Application

• As a reference standard in analytical chemistry for quality control and method validation in pharmaceutical research.
• As a key pharmacological tool in microbiological studies to investigate mechanisms of action against resistant bacterial strains.
• In medicinal chemistry research for the synthesis and structure-activity relationship (SAR) study of novel antibiotic derivatives.
• As a biochemical precursor in the development of new anti-infective agents and therapeutic candidates.
• For use in academic and industrial R&D programs focused on combating antibiotic resistance.

Basic Information

Product Name	Polyketomycin
CAS No.	200625-47-4
Molecular Formula	C₄₂H₅₄O₁₇
Molecular Weight	830.87 g/mol
Synonyms	Polyketomycin; Antibiotic BE-14106; BE-14106; (1R,2R,3S,4S,5R,6R,7S,8S,9S,10R,11S,12S,13R,14S,15R,16S,17R,18S,19S,20R,21S,22S,23R,24S,25R,26S,27S,28R,29S,30S,31R,32S,33R,34S,35R,36S,37S,38R,39S,40S,41R,42S)-42-[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36,38,40-icosaoxapentatetracontane-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39,41-heneicosaone
EINECS	Contact for details

Quality Control

Our Polyketomycin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Biological Activity (MIC)	Reported per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.