Description

2-(3,4-Difluoro-Phenyl)-n-Hydroxy-Acetamidine is a high-purity organic intermediate featuring a difluorophenyl moiety and a hydroxyacetamidine functional group. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the bioactivity of the difluorophenyl group.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Ligand and Chelator Precursor: The hydroxyacetamidine group can be utilized to develop novel ligands for catalysis or metal chelation applications.
• Fine Chemical Production: Employed in multi-step syntheses to produce complex, high-value specialty chemicals.

Basic Information

Product Name	2-(3,4-Difluoro-Phenyl)-n-Hydroxy-Acetamidine
CAS No.	200504-48-9
Molecular Formula	C8H8F2N2O
Molecular Weight	186.16 g/mol
Synonyms	N-Hydroxy-2-(3,4-difluorophenyl)acetamidine; 2-(3,4-Difluorophenyl)-N-hydroxyethanimidamide; 200504-48-9; (3,4-Difluorophenyl)(hydroxyimino)acetonitrile intermediate; Hydroxyamidine derivative
EINECS	Contact for details

Quality Control

Our 2-(3,4-Difluoro-Phenyl)-n-Hydroxy-Acetamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.