Description

Oxiranecarboxamide, 3-Methyl-2-(1-Methylethyl)-, (2R,3S)- (9Ci) is a high-purity, stereochemically defined chiral epoxide derivative, serving as a critical advanced pharmaceutical intermediate and synthetic building block. Its precise stereochemistry and reactive oxirane ring make it invaluable for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of proprietary drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators with enhanced activity and selectivity.
• Asymmetric Catalysis Research: Used as a test substrate or ligand precursor in the development of new chiral catalysts and methodologies.
• Material Science: Monomer or cross-linking agent in the production of specialized polymers and resins with tailored thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule assembly under cGMP guidelines.
• Academic & Industrial R&D: Utilized in research laboratories for exploring novel organic reactions and synthesizing complex natural product analogs.

Basic Information

Item	Details
Product Name	Oxiranecarboxamide, 3-Methyl-2-(1-Methylethyl)-, (2R,3S)- (9Ci)
CAS No.	200356-09-8
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(2R,3S)-3-Methyl-2-(1-methylethyl)oxiranecarboxamide; (2R,3S)-3-Isopropyl-2-methylglycidamide; (2R,3S)-2-Isopropyl-3-methyloxiranecarboxamide; 3-Methyl-2-(1-methylethyl)oxiranecarboxamide, (2R,3S)-; Chiral glycidamide derivative; (2R,3S)-Epoxyisobutyramide; (2R,3S)-2-Methyl-3-isopropyloxiranecarboxamide; (2R,3S)-MIOCA
EINECS	Contact for details

Quality Control

Every batch of our chiral epoxide intermediate is produced and tested under a strict quality management system. Standard quality parameters include chiral purity (enantiomeric excess) verification by chiral HPLC, identity confirmation by FT-IR and NMR, and stringent control of related substances. A comprehensive Certificate of Analysis (COA) detailing assay, purity, and physical characteristics is provided with each shipment to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.