Description

3-Carbomethoxy-4-Hydroxyphenylglyoxal Hydrate is a specialized organic compound featuring a glyoxal moiety and a phenolic ester group, making it a valuable synthon for complex chemical synthesis. Its primary value lies in its bifunctional reactivity, serving as a key intermediate in the production of advanced pharmaceutical compounds and fine chemicals. This product is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex heterocyclic or fused ring systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require specific aromatic-aldehyde functionalities.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and advanced organic materials where the glyoxal group enables further condensation or cyclization reactions.
• Research & Development: Employed in academic and industrial R&D labs for methodological studies in organic synthesis, including cross-coupling and heterocycle formation.
• Chemical Biology Probes: Potential use in developing molecular probes and tags due to its reactive carbonyl groups that can form conjugates with biomolecules.

Basic Information

Item	Details
Product Name	3-Carbomethoxy-4-Hydroxyphenylglyoxal Hydrate
CAS No.	29754-58-3
Molecular Formula	C10H10O6 • xH2O
Molecular Weight	226.18 g/mol (Anhydrous basis)
Synonyms	Methyl 2,4-dihydroxy-α-oxobenzeneacetate; (3-Carbomethoxy-4-hydroxyphenyl)glyoxal hydrate; 4-Hydroxy-3-methoxycarbonylphenylglyoxal hydrate; Methyl 4-hydroxy-α-oxobenzeneacetate; 2,4-Dihydroxy-α-oxobenzeneacetic acid methyl ester; Glyoxylic acid, (4-hydroxy-3-methoxycarbonylphenyl)-, hydrate
EINECS	Contact for details

Quality Control

Every batch of 3-Carbomethoxy-4-Hydroxyphenylglyoxal Hydrate is produced and tested under strict quality management protocols to ensure consistency and reliability for industrial use. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material is suitable for use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.