Description

Grayanotoxane-3β,5,6β,7α,10,16-Hexol is a highly functionalized diterpenoid compound of significant interest in natural product chemistry and pharmacology. This complex polyol structure serves as a key intermediate and reference standard for the study of grayanotoxin derivatives, which are known for their potent biological activities. It is primarily utilized by research institutions and pharmaceutical development companies engaged in neuropharmacology, toxicology, and the synthesis of novel bioactive molecules.

Application

• Pharmacological Research Standard: Acts as a critical reference compound for studying the structure-activity relationships (SAR) of grayanotoxin analogs and their effects on sodium channels.
• Natural Product Isolation & Analysis: Used as a benchmark in the isolation, purification, and analytical characterization (e.g., HPLC, LC-MS) of related diterpenoids from plant sources like Rhododendron species.
• Organic Synthesis Intermediate: Serves as a sophisticated starting material or intermediate for the semi-synthesis of specialized grayanotoxin derivatives for biological screening.
• Toxicology Studies: Employed in controlled laboratory studies to understand the mechanisms of action and toxicological profiles of grayanotoxin-class compounds.
• Biochemical Probe Development: Utilized in the development of molecular probes to investigate voltage-gated ion channel function and modulation.
• Quality Control & Method Development: Functions as a high-purity standard for developing and validating analytical methods in quality control laboratories serving the botanical extract and pharmaceutical industries.

Basic Information

Product Name	Grayanotoxane-3β,5,6β,7α,10,16-Hexol
CAS No.	29708-82-5
Molecular Formula	C20H34O6
Molecular Weight	370.48 g/mol
Synonyms	Grayanotoxane-3,5,6,7,10,16-hexol; 3β,5,6β,7α,10,16-Hexahydroxygrayanotaxane; Grayanotoxin XVIII; Grayanotoxane hexol; (3β,5β,6β,7α,10β,16β)-Grayanotaxane-3,5,6,7,10,16-hexol; Acetylandromedol aglycone; Rhodojaponin VI aglycone
EINECS	Contact for details

Quality Control

Our Grayanotoxane-3β,5,6β,7α,10,16-Hexol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for reference materials, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.