Description

1,4-Dichloro-2-Iodobenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring chlorine and iodine substituents in specific positions, makes it a versatile intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for cross-coupling reactions and other sophisticated chemical transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring specific halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where its halogen pattern contributes to biological activity.
• Material Science Research: Serves as a building block for organic electronic materials, liquid crystals, and specialty polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactivity of the iodine substituent.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.
• Ligand and Catalyst Preparation: Used in the synthesis of specialized ligands and organometallic catalysts.

Basic Information

Product Name	1,4-Dichloro-2-Iodobenzene
CAS No.	29682-41-5
Molecular Formula	C6H3Cl2I
Molecular Weight	272.90 g/mol
Synonyms	2-Iodo-1,4-dichlorobenzene; 1,4-Dichloro-2-iodobenzene; 2,5-Dichloroiodobenzene; Benzene, 1,4-dichloro-2-iodo-; p-Dichloro-o-iodobenzene; 4-Chloro-2-iodo-1-chlorobenzene; 1-Chloro-4-chloro-2-iodobenzene
EINECS	Contact for details

Quality Control

Our 1,4-Dichloro-2-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.