Description

1-(5-Fluoro-Thiophen-2-Yl)-Ethanone is a high-purity fluorinated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters because it serves as a versatile and critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that need it include pharmaceutical R&D for creating new active pharmaceutical ingredients (APIs), agrochemical manufacturers developing novel crop protection agents, and specialty chemical producers engaged in material science and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced organic electronic materials due to its thiophene backbone.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Acts as a building block for various specialty and performance chemicals requiring a fluorinated thiophene moiety.

Basic Information

Product Name	1-(5-Fluoro-Thiophen-2-Yl)-Ethanone
CAS No.	29669-44-1
Molecular Formula	C6H5FOS
Molecular Weight	144.17 g/mol
Synonyms	2-Acetyl-5-fluorothiophene; 5-Fluoro-2-acetylthiophene; 1-(5-Fluorothiophen-2-yl)ethan-1-one; 5-Fluoro-2-thienyl methyl ketone; Ethanone, 1-(5-fluoro-2-thienyl)-; 2-Thienyl, 5-fluoro-, methyl ketone; 5-Fluoro-2-acetylthiophene; 5-Fluoro-2-thiophenecarbaldehyde, methyl ketone derivative
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoro-Thiophen-2-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients in regulated industries. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.