Description

(1R,4As,5R,8As)-5-[(R)-3-Methyl-4-Carboxybutyl]-1,4A-Dimethyl-6-Methylenedecalin-1-Carboxylic Acid CAS NO 29455-26-3 is a high-purity, stereochemically defined diterpenoid carboxylic acid derivative. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical development companies working on novel therapeutic agents, particularly in the areas of anti-inflammatory and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates.
• Chemical Synthesis Building Block: Used in stereoselective synthesis to construct complex natural product analogs and diterpenoid frameworks.
• Biochemical Research: Employed as a reference standard or probe in enzymatic and receptor binding studies.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(1R,4As,5R,8As)-5-[(R)-3-Methyl-4-Carboxybutyl]-1,4A-Dimethyl-6-Methylenedecalin-1-Carboxylic Acid
CAS No.	29455-26-3
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	5-[(R)-3-Methyl-4-Carboxybutyl]-1,4a-dimethyl-6-methylenedecahydronaphthalene-1-carboxylic Acid; (1R,4aR,5R,8aR)-5-[(2R)-3-Methyl-4-Carboxybutyl]-1,4a-dimethyl-6-methylenedecalin-1-carboxylic Acid; Diterpenoid Carboxylic Acid Derivative; Abietic Acid Derivative; Rosin Acid Derivative; CAS 29455-26-3
EINECS	Contact for details

Quality Control

Our (1R,4As,5R,8As)-5-[(R)-3-Methyl-4-Carboxybutyl]-1,4A-Dimethyl-6-Methylenedecalin-1-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.