Description

5'-Fluoro-2'-Methylacetophenone is a high-purity fluorinated aromatic ketone building block essential for advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a key intermediate for creating more complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for applications such as active pharmaceutical ingredient (API) development and novel crop protection agent synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those requiring a fluorinated aromatic moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and advanced organic materials that benefit from fluorinated components.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and verification in pharmaceutical and chemical manufacturing.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic chemistry, including cross-coupling reactions and fluorination chemistry research.

Basic Information

Product Name	5'-Fluoro-2'-Methylacetophenone
CAS No.	29427-49-4
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	1-(5-Fluoro-2-methylphenyl)ethan-1-one; 5'-Fluoro-2'-methylacetophenone; 1-Acetyl-5-fluoro-2-methylbenzene; 5-Fluoro-2-methylacetophenone; 2-Methyl-5-fluoroacetophenone; 2'-Methyl-5'-fluoroacetophenone; 5-Fluoro-o-methylacetophenone; (5-Fluoro-2-methylphenyl) methyl ketone
EINECS	Contact for details

Quality Control

Our 5'-Fluoro-2'-Methylacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity confirmation, and impurity profiles. While typically supplied as a standard R&D grade, production can be aligned with cGMP guidelines for advanced project stages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.