Description

L-Methylphenidate is the pharmacologically active enantiomer of the central nervous system stimulant methylphenidate. This high-purity compound is critical for the development and production of enantiomerically pure pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on advanced neuropharmacology and the treatment of attention deficit disorders. Consistent quality and reliable supply are paramount for ensuring the efficacy and safety of the final drug product.

Application

• Active Pharmaceutical Ingredient (API) in enantiomerically pure medications for Attention Deficit Hyperactivity Disorder (ADHD).
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Research Chemical in neuropharmacological studies investigating dopaminergic and noradrenergic systems.
• Process Development for the synthesis of novel drug derivatives and delivery systems.
• Formulation Development for controlled-release and other advanced dosage forms.

Basic Information

Product Name	L-Methylphenidate
CAS No.	29419-95-2
Molecular Formula	C₁₄H₁₉NO₂
Molecular Weight	233.31 g/mol
Synonyms	(-)-Methylphenidate; (R,R)-Methylphenidate; d-threo-Methylphenidate; Dexmethylphenidate; Focalin (trade name base); (2R,2'R)-Methyl 2-phenyl-2-(piperidin-2-yl)acetate; L-threo-Methyl α-phenyl-2-piperidineacetate
EINECS	Contact for details

Quality Control

Our L-Methylphenidate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles to support our clients' regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 99.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.5%
Related Substances (HPLC)	Individual impurity ≤ 0.1%, Total impurities ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.