Description

10-[2-(3-Methyl-3H-Diazirin-3-Yl)Ethyl]-10H-Phenothiazine is a specialized heterocyclic organic compound that combines a phenothiazine core with a photoactivatable diazirine moiety. This unique structure makes it a critical intermediate and reagent in advanced chemical synthesis and life science research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications requiring photoaffinity labeling and cross-linking studies.

Application

• Photoaffinity Labeling Probes: Acts as a key precursor for synthesizing probes to study protein-ligand interactions, receptor binding sites, and enzyme active sites.
• Bioconjugation and Cross-linking: Used to create covalent bonds between biomolecules under mild UV light activation for structural biology and diagnostic assay development.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Polymer and Material Science: Incorporated into polymers and advanced materials to introduce photo-reactive properties for surface modification and functional material design.
• Agrochemical Research: Employed in the development of new pesticides and herbicides through mechanism-of-action studies.
• Chemical Biology Tool Development: Essential for creating chemical tools to map metabolic pathways and investigate cellular processes.

Basic Information

Product Name	10-[2-(3-Methyl-3H-Diazirin-3-Yl)Ethyl]-10H-Phenothiazine
CAS No.	29205-52-5
Molecular Formula	C₁₇H₁₅N₃S
Molecular Weight	293.39 g/mol
Synonyms	3-[2-(10H-Phenothiazin-10-yl)ethyl]-3-methyldiazirine; 10H-Phenothiazine, 10-[2-(3-methyl-3H-diazirin-3-yl)ethyl]-; Phenothiazine diazirine derivative; 3-Methyl-3-[2-(phenothiazin-10-yl)ethyl]diazirine; Photoactivatable phenothiazine; Diazirinylphenothiazine; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 10-[2-(3-Methyl-3H-Diazirin-3-Yl)Ethyl]-10H-Phenothiazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, all handling and storage must be performed under conditions that strictly protect the material from light exposure to maintain stability and efficacy.

Specification

Item	Specification
Appearance	Light yellow to yellow powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.