Description

(S)-3,4,5,6,7,8-Hexahydro-1-[(4-Methoxyphenyl)Methyl](1H)-Isoquinoline-2-Carbaldehyde is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters because it serves as a critical building block for the development of complex, biologically active molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and receptor modulators.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or reagent in stereoselective reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals, catalysts, and ligands for chemical processes.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel, optically active crop protection agents.
• Academic & Institutional Research: Serves as a valuable compound for methodological development in organic chemistry and catalysis at universities and research institutes.

Basic Information

Product Name	(S)-3,4,5,6,7,8-Hexahydro-1-[(4-Methoxyphenyl)Methyl](1H)-Isoquinoline-2-Carbaldehyde
CAS No.	29144-31-8
Molecular Formula	C18H23NO2
Molecular Weight	285.38 g/mol
Synonyms	(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline-2-carboxaldehyde; (S)-1-[(4-Methoxyphenyl)methyl]-3,4,5,6,7,8-hexahydro-1H-isoquinoline-2-carbaldehyde; (S)-N-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline-2-carboxaldehyde; (S)-1-(p-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline-2-carbaldehyde; (S)-PMB-IQ-2-CHO; (S)-Hexahydro-1-[(4-methoxyphenyl)methyl]isoquinoline-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), with enantiomeric excess (ee) specifications available to meet specific project requirements. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.