Description

2',5'-Difluoropropiophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which can dramatically influence the electronic properties, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in developing new herbicides and pesticides, where the difluoro motif can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated organic electronic materials due to its ability to modify molecular polarity and packing.
• Advanced Organic Synthesis: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce the difluorophenyl moiety into more complex architectures.
• Fluorine Chemistry Studies: Used as a model compound in academic and industrial research to study the effects of aromatic fluorine substitution.

Basic Information

Product Name	2',5'-Difluoropropiophenone
CAS No.	29112-90-1
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-(2,5-Difluorophenyl)propan-1-one; 2,5-Difluoropropiophenone; Propiophenone, 2',5'-difluoro-; 2,5-Difluorophenyl Ethyl Ketone; α-Ethyl-2,5-difluorobenzene methanol
EINECS	Contact for details

Quality Control

Our 2',5'-Difluoropropiophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our commitment to cGMP and ISO standards ensures reliable and consistent material for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.