Description

n-tert-Butyl-4-Chlorobenzenesulfonamide is a specialized organic sulfonamide derivative, serving as a crucial synthetic intermediate and building block in advanced chemical synthesis. Its value lies in the unique steric and electronic properties imparted by the tert-butyl and chlorophenyl groups, which are essential for constructing complex molecular architectures. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or additive in the development of specialty polymers, resins, and advanced functional materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for enzyme inhibitors.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the sulfonamide functional group under controlled conditions.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized colorants and photographic chemicals.

Basic Information

Product Name	n-tert-Butyl-4-Chlorobenzenesulfonamide
CAS No.	29083-03-2
Molecular Formula	C10H14ClNO2S
Molecular Weight	247.74 g/mol
Synonyms	4-Chloro-N-(1,1-dimethylethyl)benzenesulfonamide; 4-Chloro-N-tert-butylbenzenesulfonamide; N-(tert-Butyl)-4-chlorobenzenesulfonamide; p-Chloro-N-tert-butylbenzenesulfonamide; Benzenesulfonamide, 4-chloro-N-(1,1-dimethylethyl)-; t-Butyl 4-chlorobenzenesulfonamide; 4-Chlorobenzenesulfonamide, N-tert-butyl-; N-t-Butyl-4-chlorobenzenesulfonamide
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-4-Chlorobenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.