Description

4-Mercaptocinnamic Acid is a specialized organic compound featuring both a thiol (-SH) and a carboxylic acid (-COOH) functional group on a cinnamic acid backbone. This unique bifunctional structure makes it a valuable building block and intermediate in advanced organic synthesis and materials science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting cysteine proteases or requiring thiol conjugation.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage its reactive thiol group.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with enhanced adhesion, self-healing, or responsive properties.
• Bioconjugation & Protein Labeling: The thiol group enables selective attachment to biomolecules (e.g., peptides, proteins) for diagnostic and therapeutic applications.
• Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and surface coatings.
• Chemical Synthesis Reagent: Functions as a versatile reagent for Michael additions, thiol-ene "click" chemistry, and other organic transformations.

Basic Information

Product Name	4-Mercaptocinnamic Acid
CAS No.	28995-22-4
Molecular Formula	C9H8O2S
Molecular Weight	180.22 g/mol
Synonyms	(E)-3-(4-Sulfanylphenyl)acrylic acid; 3-(4-Mercaptophenyl)-2-propenoic acid; 4-Thiolcinnamic acid; p-Mercaptocinnamic acid; 4-Sulfanylcinnamic acid; (2E)-3-(4-Sulfanylphenyl)prop-2-enoic acid; 3-(4-Sulfanylphenyl)acrylic acid
EINECS	Contact for details

Quality Control

Our 4-Mercaptocinnamic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation and light, minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.