Description

Oridonin CAS NO 28957-04-2 is a bioactive ent-kaurane diterpenoid compound, primarily isolated from the traditional Chinese herb *Rabdosia rubescens*. This natural product is of significant commercial and research interest due to its potent and multi-targeted biological activities. It is a critical raw material for the pharmaceutical, nutraceutical, and life science research industries, where it is investigated for its promising therapeutic properties.

Application

• Pharmaceutical Intermediate: Serves as a key starting material or active pharmaceutical ingredient (API) in the development of novel anti-cancer and anti-inflammatory drugs.
• Biomedical Research Reagent: Used in academic and industrial laboratories to study mechanisms of apoptosis, autophagy, and cell cycle regulation in various disease models.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements for its potential health-modulating and wellness-supporting benefits.
• Cosmeceutical Ingredient: Applied in advanced skincare formulations targeting inflammation and oxidative stress due to its bioactive properties.
• Reference Standard: Employed as a high-purity chromatographic standard for quality control and analytical method development in herbal extract and pharmaceutical analysis.

Basic Information

Product Name	Oridonin
CAS No.	28957-04-2
Molecular Formula	C₂₀H₂₈O₆
Molecular Weight	364.43 g/mol
Synonyms	Rubescensin; Isodonol; 7,20-Epoxy-1α,6β,7α,14β-tetrahydroxy-7α,20-epoxykaur-16-en-15-one; NSC-267012; 1,6,7,14-Tetrahydroxy-7α,20-epoxy-ent-kaur-16-en-15-one; Rabdosin B
EINECS	Contact for details

Quality Control

Our Oridonin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.