Description

(1R)-1,1Aβ,2,4,5,6,6A,7Aβ-Octahydro-1,6β,6Aβ-Trimethyl-1α,2Aα-Methano-2Ah-Cyclopropa[B]Naphthalen-7(3H)-One is a high-purity, complex tricyclic ketone of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceutical actives and fine chemicals. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and specialty chemical manufacturers engaged in the synthesis of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly in steroid-like or terpenoid-based drug discovery programs.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Fragrance & Flavor Chemistry: Serves as a potential intermediate for the synthesis of high-value, complex odorants and flavor compounds due to its intricate tricyclic structure.
• Material Science Research: Investigated as a monomer or building block for the development of novel organic frameworks and specialty polymers with unique properties.
• Agrochemical Development: Used in research for creating new active ingredients with complex, bioactive ring systems for crop protection.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry, including novel ring-forming reactions and stereochemistry investigations.

Basic Information

Product Name	(1R)-1,1Aβ,2,4,5,6,6A,7Aβ-Octahydro-1,6β,6Aβ-Trimethyl-1α,2Aα-Methano-2Ah-Cyclopropa[B]Naphthalen-7(3H)-One
CAS No.	28895-15-0
Molecular Formula	C15H22O
Molecular Weight	218.33 g/mol
Synonyms	(1R)-1,1aβ,2,4,5,6,6aβ,7aβ-Octahydro-1,6β,6aβ-trimethyl-1α,2aα-methano-2ah-cyclopropa[b]naphthalen-7(3H)-one; 7-Oxotricyclo[4.4.0.02,8]decane, 1,5,5,8a-tetramethyl-, (1R,2R,4aR,8aS)-rel-; Tricyclo[4.4.0.02,8]decan-7-one, 1,5,5,8a-tetramethyl-, (1R,2R,4aR,8aS)-rel-; A complex tricyclic ketone intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, chiral analysis, and NMR spectroscopy. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.