Description

2β,3β-Epoxy-6β,7α-(Isopropylidenebisoxy)Grayanotoxane-5,10,16-Triol CAS NO 28836-76-2 is a highly functionalized grayanotoxane diterpenoid derivative, characterized by its unique epoxy and isopropylidene-protected diol functionalities. This compound serves as a critical advanced intermediate in synthetic organic chemistry, enabling the construction of complex molecular architectures. It is primarily sought after by researchers and developers in the pharmaceutical and agrochemical sectors for the synthesis of novel bioactive molecules and natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting neurological and cardiovascular pathways.
• Natural Product Synthesis: Advanced precursor in the total or semi-synthesis of complex grayanane diterpenoids and related natural products.
• Medicinal Chemistry Research: Used to explore structure-activity relationships (SAR) by modifying the grayanotoxane core for new biological activities.
• Agrochemical Development: Serves as a starting material for creating new plant protection agents with unique modes of action.
• Biochemical Tool Compound: Potential use in pharmacological studies to investigate ion channel modulation and other cellular mechanisms.
• Reference Standard: High-purity material for analytical method development and quality control in related compound manufacturing.

Basic Information

Product Name	2β,3β-Epoxy-6β,7α-(Isopropylidenebisoxy)Grayanotoxane-5,10,16-Triol
CAS No.	28836-76-2
Molecular Formula	C20H30O7
Molecular Weight	382.45 g/mol
Synonyms	2β,3β-Epoxy-6β,7α-(isopropylidenebisoxy)grayanotoxane-5,10,16-triol; (2β,3β,5β,6β,7α,10β,16β)-2,3-Epoxy-6,7-[(1-methylethylidene)bis(oxy)]grayanotoxane-5,10,16-triol; Grayanotoxane-5,10,16-triol, 2,3-epoxy-6,7-(isopropylidenebisoxy)-, (2β,3β,5β,6β,7α,10β,16β)-; 6β,7α-O-Isopropylidene-2β,3β-epoxygrayanotoxane-5β,10β,16β-triol; Advanced Grayanotoxin Derivative; Grayanotoxane Epoxy Diol Acetonide
EINECS	Contact for details

Quality Control

Our 2β,3β-Epoxy-6β,7α-(Isopropylidenebisoxy)Grayanotoxane-5,10,16-Triol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider storage under inert atmosphere. The compound is moisture-sensitive (hygroscopic).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.