Description

5-Nitro-3-Carboxybenzisoxazole is a high-purity, multi-functional heterocyclic building block of significant commercial and research interest. Its value lies in its unique molecular structure, which serves as a versatile precursor for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for R&D chemists and process development teams working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its nitro and carboxylic acid functionalities.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic frameworks for material science and chemical research.
• Dye and Pigment Precursor: Serves as an intermediate in the manufacture of specialized dyes and high-performance pigments.
• Coordination Chemistry Ligand: The carboxylic acid group allows it to act as a ligand for metal complexes in catalytic applications.
• Research & Development: A valuable tool for academic and industrial research in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	5-Nitro-3-Carboxybenzisoxazole
CAS No.	28691-51-2
Molecular Formula	C8H4N2O5
Molecular Weight	208.13 g/mol
Synonyms	3-Carboxy-5-nitrobenzisoxazole; 5-Nitro-1,2-benzisoxazole-3-carboxylic acid; 5-Nitrobenzisoxazole-3-carboxylic acid; 5-Nitro-3-benzisoxazolecarboxylic acid; 1,2-Benzisoxazole-3-carboxylic acid, 5-nitro-; 28691-51-2 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Nitro-3-Carboxybenzisoxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.