Description

(-)-11-Hydroxy-Delta8-Tetrahydrocannabinol is a significant hydroxylated metabolite of δ-8-THC, offering a distinct pharmacological profile for research and development. This compound is crucial for advancing scientific understanding of cannabinoid metabolism, receptor interactions, and therapeutic potential. It is primarily utilized by pharmaceutical R&D laboratories, analytical reference standard providers, and institutions conducting preclinical cannabinoid studies.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity certified reference material (CRM) for the quantification and qualification of cannabinoids and their metabolites in analytical methods.
• Metabolic Pathway Research: Used in in vitro and in vivo studies to investigate the biotransformation and pharmacokinetics of δ-8-Tetrahydrocannabinol.
• Bioactivity Profiling: Essential for assays evaluating the binding affinity, efficacy, and functional activity at cannabinoid receptors (CB1 and CB2) and other potential targets.
• Forensic and Clinical Toxicology: Employed as a calibrator or control in LC-MS/MS and GC-MS methods for the accurate detection of cannabinoid metabolites in biological matrices.
• Drug Discovery & Development: Acts as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel cannabinoid-based therapeutics.
• Academic Research: Supports university and institutional research into the physiological effects, therapeutic benefits, and safety profiles of specific cannabinoid metabolites.

Basic Information

Item	Details
Product Name	(-)-11-Hydroxy-Delta8-Tetrahydrocannabinol
CAS No.	28646-40-4
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	11-Hydroxy-δ8-THC; (-)-11-Hydroxy-δ8-tetrahydrocannabinol; 11-OH-δ8-THC; 11-Hydroxydelta8-tetrahydrocannabinol; 1-Hydroxy-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-6-ol (enantiomer); δ-8-THC-11-ol
EINECS	Contact for details

Quality Control

Our (-)-11-Hydroxy-Delta8-Tetrahydrocannabinol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label or CoA. This product is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.