Description

2-Chloro-3-Hydroxypropanal is a versatile bifunctional organic compound featuring both aldehyde and chlorohydrin groups. This unique structure makes it a valuable chiral building block and reactive intermediate for synthesizing more complex molecules. It is particularly sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various active pharmaceutical ingredients (APIs), particularly β-blockers and other cardiovascular drugs.
• Fine Chemical Synthesis: Used as a versatile building block for creating complex organic molecules, including specialty polymers, ligands, and catalysts.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, pesticides, and plant growth regulators.
• Bioconjugation Chemistry: The reactive aldehyde and chloro groups enable its use in cross-linking and modifying biomolecules for research and diagnostic applications.
• Material Science: Employed in the synthesis of functionalized polymers and resins with specific chemical properties.

Basic Information

Product Name	2-Chloro-3-Hydroxypropanal
CAS No.	28598-66-5
Molecular Formula	C3H5ClO2
Molecular Weight	108.52 g/mol
Synonyms	3-Chloro-2-hydroxypropanal; 2-Chloro-3-hydroxypropionaldehyde; Glyceraldehyde 2-chlorohydrin; 2-Chloro-3-hydroxypropan-1-al; Chlorohydroxypropanal; 3-Chloro-2-hydroxypropionaldehyde; α-Chloroglyceraldehyde; (RS)-2-Chloro-3-hydroxypropanal
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Hydroxypropanal is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.