Description

4-Chlorocinnamonitrile is a versatile aromatic nitrile building block characterized by a chlorinated cinnamyl structure. This compound matters for its role as a key synthetic intermediate in the production of fine chemicals and active pharmaceutical ingredients (APIs), enabling the introduction of both nitrile and aryl chloride functionalities. Industries such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical synthesis require this high-purity intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its reactive nitrile and chloro groups.
• Ligand and Catalyst Preparation: Acts as a starting material for creating specialized ligands used in transition metal catalysis.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals.
• Material Science Research: Utilized in the development of organic semiconductors and advanced polymeric materials.
• Cross-Coupling Reactions: Functions as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	4-Chlorocinnamonitrile
CAS No.	28446-72-2
Molecular Formula	C9H6ClN
Molecular Weight	163.60 g/mol
Synonyms	(E)-3-(4-Chlorophenyl)-2-propenenitrile; 4-Chlorocinnamnitrile; 3-(4-Chlorophenyl)acrylonitrile; (E)-4-Chlorocinnamonitrile; trans-4-Chlorocinnamonitrile; p-Chlorocinnamonitrile; 2-Propenenitrile, 3-(4-chlorophenyl)-; Cinnamonitrile, 4'-chloro-
EINECS	Contact for details

Quality Control

Our 4-Chlorocinnamonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.