Description

4-Oxo-Cyclopentane-trans-1,2-Dicarboxylic Acid Dimethyl Ester is a high-purity diester derivative of cyclopentanone, serving as a versatile and critical chiral building block in advanced organic synthesis. Its value lies in its rigid, functionalized five-membered ring structure, which is essential for constructing complex molecular architectures with precise stereochemistry. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandin analogs, nucleoside derivatives, and other bioactive molecules with defined stereocenters.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific spatial orientation for activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and specialty polymers where the trans-diester configuration imparts specific physical properties.
• Academic & R&D: Employed in methodological chemistry research, including studies on asymmetric catalysis, ring-forming reactions, and the development of new synthetic pathways.
• Material Science: Potential monomer or cross-linking agent for synthesizing specialized polyesters and polycarbonates with unique thermal and mechanical characteristics.

Basic Information

Product Name	4-Oxo-Cyclopentane-trans-1,2-Dicarboxylic Acid Dimethyl Ester
CAS No.	28269-03-6
Molecular Formula	C9H12O5
Molecular Weight	200.19 g/mol
Synonyms	trans-1,2-Bis(methoxycarbonyl)-4-cyclopentanone; Dimethyl trans-4-Oxocyclopentane-1,2-dicarboxylate; (1R,2R)-rel-4-Oxocyclopentane-1,2-dicarboxylic Acid Dimethyl Ester; trans-4-Oxocyclopentane-1,2-dicarboxylic Acid Dimethyl Ester; Cyclopentanone-4-carboxylic Acid, trans-1,2-Dimethyl Ester; 4-Ketocyclopentane-trans-1,2-dicarboxylic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our 4-Oxo-Cyclopentane-trans-1,2-Dicarboxylic Acid Dimethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.