Description

1-Cyanocyclobutanecarboxylic Acid Ethyl Ester is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring a cyclobutane ring, a nitrile group, and an ester functionality, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring constrained, four-membered ring systems for biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the cyclobutane scaffold can impart unique properties.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialized polymers with tailored thermal or mechanical properties.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to introduce the cyclobutane moiety, with the nitrile and ester groups offering handles for further functionalization.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands or organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	1-Cyanocyclobutanecarboxylic Acid Ethyl Ester
CAS No.	28246-87-9
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	Ethyl 1-Cyanocyclobutanecarboxylate; 1-Cyano-cyclobutanecarboxylic Acid Ethyl Ester; Cyclobutanecarboxylic Acid, 1-Cyano-, Ethyl Ester; Ethyl 1-Cyanocyclobutan-1-carboxylate; 1-Carbethoxy-1-cyanocyclobutane; 28246-87-9; Ethyl 1-cyanocyclobutane-1-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 1-Cyanocyclobutanecarboxylic Acid Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The product is compatible with organic solvents but should be stored separately from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.