Description

2-Bromo-1-(4-Benzyl-Phenyl)-Ethanone is a specialized brominated aromatic ketone, a key building block in advanced organic synthesis. This compound matters for its role as a versatile electrophilic reagent, enabling the introduction of functionalized acetyl groups into complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides and herbicides, where its reactive bromoacetyl moiety facilitates the creation of complex bioactive molecules.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation, labeling proteins, or modifying biomolecules for study and diagnostic applications.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including Friedel-Crafts acylation and subsequent functional group transformations.

Basic Information

Product Name	2-Bromo-1-(4-Benzyl-Phenyl)-Ethanone
CAS No.	28179-31-9
Molecular Formula	C15H13BrO
Molecular Weight	289.17 g/mol
Synonyms	2-Bromo-1-(4-benzylphenyl)ethanone; 2-Bromo-4'-benzylacetophenone; 4-Benzylphenacyl Bromide; ω-Bromo-4-benzylacetophenone; 1-(4-Benzylphenyl)-2-bromoethanone; 2-Bromo-1-(4-benzylphenyl)ethan-1-one; α-Bromo-4'-benzylacetophenone; p-Benzylphenacyl Bromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Benzyl-Phenyl)-Ethanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to consistent quality and traceability supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.