Description

1-(Ethenesulfonyl)-4-Fluorobenzene is a specialized fluorinated sulfone derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in the reactive ethenesulfonyl group, which enables efficient introduction of the vinyl sulfone moiety, a key functional group in modern synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, particularly for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drugs, especially those targeting specific enzymes via Michael addition reactions.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides that leverage the bioactivity of fluorinated sulfones.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Chemical Biology: Employed as an activity-based probe (ABP) for labeling and studying cysteine proteases and other enzymes in proteomic research.
• Organic Synthesis: A versatile reagent for constructing complex molecules through cycloaddition, conjugate addition, and other C-C bond forming reactions.

Basic Information

Product Name	1-(Ethenesulfonyl)-4-Fluorobenzene
CAS No.	28122-14-7
Molecular Formula	C8H7FO2S
Molecular Weight	186.20 g/mol
Synonyms	4-Fluoro-1-(vinylsulfonyl)benzene; 4-Fluorophenyl vinyl sulfone; p-Fluorophenyl vinyl sulfone; 1-Fluoro-4-(vinylsulfonyl)benzene; Vinyl 4-fluorophenyl sulfone; (4-Fluorophenyl)ethenesulfone; 28122-14-7; 4-Fluorophenyl vinylsulfone
EINECS	Contact for details

Quality Control

Our production of 1-(Ethenesulfonyl)-4-Fluorobenzene adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, with specifications tailored to meet the rigorous demands of research and process development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.