Description

1-(2-Bromophenyl)-Cyclobutanecarbonitrile is a versatile brominated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a cyclobutane ring and a strategically positioned bromine atom, makes it a critical precursor for constructing complex, three-dimensional molecular scaffolds. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of advanced organic electronic materials and liquid crystals due to its rigid, substituted aromatic core.
• Chemical Biology Probes: Useful for creating tagged molecules and activity-based probes for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-(2-Bromophenyl)-Cyclobutanecarbonitrile
CAS No.	28049-62-9
Molecular Formula	C11H10BrN
Molecular Weight	236.11 g/mol
Synonyms	2-Bromo-α-cyclobutylbenzenecarbonitrile; (2-Bromophenyl)cyclobutanecarbonitrile; 1-(2-Bromophenyl)cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(2-bromophenyl)-; α-Cyclobutyl-2-bromobenzonitrile; 2-Bromobenzeneacetonitrile, α-cyclobutyl-; 1-(o-Bromophenyl)cyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(2-Bromophenyl)-Cyclobutanecarbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support compliance with global regulatory frameworks, and custom purity grades (e.g., >98%, >99%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.