Description

1-(4-Chlorophenyl)-1-Cyclobutanecarbonitrile is a versatile and high-purity organic nitrile building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a chlorophenyl and a cyclobutane ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Used in organometallic chemistry for the preparation of specialized ligands and catalysts used in asymmetric synthesis.
• Material Science Research: Acts as a monomer or precursor in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Scale-Up: Supplied for contract research organizations (CROs) and chemical development companies for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	1-(4-Chlorophenyl)-1-Cyclobutanecarbonitrile
CAS No.	28049-61-8
Molecular Formula	C11H10ClN
Molecular Weight	191.66 g/mol
Synonyms	4-Chloro-α-(1-cyanocyclobutyl)benzene; 1-(p-Chlorophenyl)-1-cyclobutanecarbonitrile; 1-Cyclobutyl-1-(4-chlorophenyl)methanenitrile; (4-Chlorophenyl)(1-cyanocyclobutyl)methane; α-(1-Cyanocyclobutyl)-4-chlorobenzene; p-Chloro-α-(1-cyanocyclobutyl)benzene
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-1-Cyclobutanecarbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.