Description

1-(2-Chlorophenyl)Cyclobutanecarbonitrile is a versatile and high-value organic intermediate characterized by its unique cyclobutane ring fused with a chlorinated aromatic nitrile group. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical sector where it serves as a key building block for active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development of novel therapeutic agents and advanced material science.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its chlorophenyl moiety.
• Material Science Research: Serves as a monomer or building block for developing specialized polymers and liquid crystals with unique optical properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex carbon skeletons and studying cyclobutane ring reactions.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-(2-Chlorophenyl)Cyclobutanecarbonitrile
CAS No.	28049-59-4
Molecular Formula	C11H10ClN
Molecular Weight	191.66 g/mol
Synonyms	2-Chloro-α-(cyclobutylidene)benzenecetonitrile; 1-(2-Chlorophenyl)cyclobutanecarbonitrile; (2-Chlorophenyl)(cyclobutylidene)acetonitrile; Cyclobutanecarbonitrile, 1-(2-chlorophenyl)-; α-(Cyclobutylidene)-2-chlorobenzeneacetonitrile; 2-Chlorobenzylidenecyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chlorophenyl)Cyclobutanecarbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, ensuring full traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.