Description

Tetraethyl 4,4'-Biphenylenebisphosphonate is a high-purity organophosphorus compound characterized by its biphenyl-linked bisphosphonate ester structure. This compound serves as a versatile and critical chemical intermediate in advanced synthesis, particularly valued for its role in constructing complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require reliable, high-quality building blocks for drug discovery, ligand synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bisphosphonate-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the development of herbicides, plant growth regulators, and other crop protection agents with phosphonate functionalities.
• Ligand and Catalyst Preparation: Serves as a starting material for creating chelating ligands used in catalysis and metal ion sequestration.
• Polymer and Materials Chemistry: Incorporated as a monomer or cross-linking agent to impart flame retardancy or modify the thermal and mechanical properties of polymers.
• Organic Synthesis Building Block: Employed in coupling reactions and as a scaffold for constructing complex organic molecules in research and development.
• Coordination Chemistry: Utilized to synthesize metal-organic frameworks (MOFs) or complexes for various industrial and research applications.

Basic Information

Product Name	Tetraethyl 4,4'-Biphenylenebisphosphonate
CAS No.	28036-07-9
Molecular Formula	C20H28O6P2
Molecular Weight	426.37 g/mol
Synonyms	4,4'-Biphenylylenebisphosphonic Acid Tetraethyl Ester; Tetraethyl [1,1'-Biphenyl]-4,4'-diylbis(phosphonate); 4,4'-Biphenylenebis(phosphonic Acid) Tetraethyl Ester; Diethyl ((([1,1'-Biphenyl]-4,4'-diylbis(oxy))bis(phosphorylidene))bis(methylene)) Dicarbonate (alternative IUPAC); Biphenyl-4,4'-diylbis(phosphonic Acid) Tetraethyl Ester; Phosphonic Acid, P,P'-(1,1'-Biphenyl)-4,4'-diyl P,P,P',P'-Tetraethyl Ester
EINECS	Contact for details

Quality Control

Our Tetraethyl 4,4'-Biphenylenebisphosphonate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets exacting specifications for use as a fine chemical intermediate. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.