Description

Megalomicin A CAS NO 28022-11-9 is a macrolide antibiotic belonging to the megalomicin complex, primarily produced by *Micromonospora* species. This compound is valued for its potent antibacterial activity, particularly against Gram-positive bacteria and certain mycobacteria. It serves as a critical reference standard and active pharmaceutical ingredient (API) for research and development in the pharmaceutical and biotechnology sectors, supporting the discovery of new antimicrobial agents and the study of bacterial resistance mechanisms.

Application

• Pharmaceutical research and development as a reference standard for analytical methods.
• Active Pharmaceutical Ingredient (API) in the formulation of investigational antibiotic drugs.
• Biochemical research to study the mechanism of action of macrolide antibiotics.
• Microbiology studies for evaluating antibacterial efficacy against specific bacterial strains.
• Use in veterinary pharmaceutical research for potential applications.
• Production of high-purity chemical derivatives for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Megalomicin A
CAS No.	28022-11-9
Molecular Formula	C39H65NO14
Molecular Weight	771.93 g/mol
Synonyms	Megalomicin A1; Antibiotic XK-41-1; Megalomicin A complex; 6-Deoxy-13-cyclopentyl-13-demethyl-5-O-mycaminosyltylonolide; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our Megalomicin A is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.