Description

14,18-Epoxy-3-Hydroxy-5-Oxoophiobola-7,19-Dien-25-Oic Acid is a complex, high-purity ophiobolin derivative, a class of compounds known for their significant biological activity. This compound is valued as a critical advanced intermediate and a reference standard for research and development in life sciences. It is primarily sought by pharmaceutical R&D teams, academic research institutions, and biotech companies focused on novel therapeutic discovery.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or a reference standard in the synthesis and study of novel bioactive molecules, particularly in oncology and antimicrobial drug discovery programs.
• Biochemical Research: Used as a tool compound to investigate specific biological pathways and enzyme interactions due to its unique ophiobolin skeleton.
• Academic Studies: Employed in university and institutional labs for chemical biology research, structure-activity relationship (SAR) studies, and natural product synthesis.
• Analytical Standard: Provides a high-purity benchmark for method development and quality control in analytical laboratories using techniques like HPLC and LC-MS.
• Agrochemical Research: Investigated for potential use as a lead compound in developing new plant protection agents, leveraging the natural bioactivity of ophiobolins.

Basic Information

Product Name	14,18-Epoxy-3-Hydroxy-5-Oxoophiobola-7,19-Dien-25-Oic Acid
CAS No.	27975-44-6
Molecular Formula	C25H34O5
Molecular Weight	414.53 g/mol
Synonyms	3-Hydroxy-14,18-epoxy-5-oxoophiobola-7,19-dien-25-oic acid; Ophiobolin I; 6-epi-Ophiobolin I; (3S,4R,5R,6R,10S,14R)-3-Hydroxy-14,18-epoxy-5-oxoophiobola-7,19-dien-25-oic acid; 14,18-Epoxy-3-hydroxy-5-oxoophiobola-7,19-diene-25-carboxylic acid; Ophiobolin derivative; 27975-44-6
EINECS	Contact for details

Quality Control

Our 14,18-Epoxy-3-Hydroxy-5-Oxoophiobola-7,19-Dien-25-Oic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR, and MS for structural confirmation, to ensure it meets the exacting standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.