Description

3-[(4-Fluorophenyl)Methyl]-4,5-Dihydro-5-[(2-Propynyloxy)Methyl]-2(3H)-Furanone is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a furanone core with fluorophenyl and propargyl ether substituents, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Chemical Biology Probe Development: The alkyne (propynyl) handle allows for "click chemistry" applications, enabling the tagging and study of biological molecules.
• Material Science Research: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored optical or electronic properties.
• Academic & Contract Research: A critical reagent for methodological studies in organic chemistry, including catalysis and novel ring-forming reactions.

Basic Information

Product Name	3-[(4-Fluorophenyl)Methyl]-4,5-Dihydro-5-[(2-Propynyloxy)Methyl]-2(3H)-Furanone
CAS No.	27850-30-2
Molecular Formula	C15H15FO3
Molecular Weight	262.28 g/mol
Synonyms	5-[(Prop-2-yn-1-yloxy)methyl]-3-[(4-fluorophenyl)methyl]dihydrofuran-2(3H)-one; 3-(4-Fluorobenzyl)-5-(prop-2-yn-1-yloxymethyl)dihydrofuran-2(3H)-one; 3-(p-Fluorobenzyl)-5-(propargyloxymethyl)-γ-butyrolactone; 5-(Propargyloxymethyl)-3-(4-fluorobenzyl)dihydrofuran-2(3H)-one; Fluorinated Furanone Derivative; Propargyl Ether Furanone; Lactone Intermediate 27850-30-2
EINECS	Contact for details

Quality Control

Our production of 3-[(4-Fluorophenyl)Methyl]-4,5-Dihydro-5-[(2-Propynyloxy)Methyl]-2(3H)-Furanone adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting cGMP-compliant research and development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames due to the presence of the alkyne functional group. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.