Description

4-Chloro-3-oxobutyric acid is a versatile chlorinated keto acid derivative that serves as a critical building block in organic synthesis. Its bifunctional structure, featuring both a reactive carbonyl and an acid group, makes it an essential intermediate for constructing complex molecular frameworks. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including statins and other therapeutic agents.
• Agrochemical Synthesis: Used as a building block for creating herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and complex organic compounds.
• Biochemical Research: Serves as a substrate or intermediate in metabolic pathway studies and enzyme research.
• Polymer Chemistry: Can be utilized to introduce functional groups into polymer chains for specialty materials.
• Cross-Coupling Reactions: Acts as an electrophile in various palladium-catalyzed and other metal-mediated coupling reactions.

Basic Information

Product Name	4-Chloro-3-oxobutyric Acid
CAS No.	27807-84-7
Molecular Formula	C4H5ClO3
Molecular Weight	136.53 g/mol
Synonyms	4-Chloroacetoacetic Acid; 3-Oxo-4-chlorobutanoic Acid; 4-Chloro-3-oxobutanoic Acid; Acetoacetic acid, 4-chloro-; Chloroacetoacetic Acid; 4-Chloro-3-ketobutyric Acid; 4-Chloroacetoacetate; NSC 403697
EINECS	248-676-9

Quality Control

Our 4-Chloro-3-oxobutyric acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.