Description

(1As)-1,1Aα,4,5,6,7,7A,7Bα-Octahydro-1,1,7β,7Aβ-Tetramethyl-2H-Cyclopropa[A]Naphthalen-2-One CAS NO 27779-52-8 is a high-purity, complex sesquiterpene ketone valued for its unique molecular structure and functional properties. This compound is a critical intermediate and building block in advanced organic synthesis, particularly for the development of fragrance molecules and pharmaceutical active ingredients. It is essential for R&D and production teams in the flavor & fragrance, pharmaceutical, and fine chemical industries seeking reliable, high-quality raw materials.

Application

• Fragrance & Flavor Synthesis: A key intermediate for creating complex, woody, and ambergris-type fragrance notes in perfumery and flavor compositions.
• Pharmaceutical Intermediates: Serves as a sophisticated chiral building block in the synthesis of novel therapeutic compounds and active pharmaceutical ingredients (APIs).
• Fine Chemical Manufacturing: Used in the production of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Research & Development: A valuable reference standard and starting material for academic and industrial research in organic chemistry and natural product synthesis.
• Aroma Chemical Production: Integral to the manufacture of high-value aroma chemicals used in consumer products, cosmetics, and personal care items.

Basic Information

Product Name	(1As)-1,1Aα,4,5,6,7,7A,7Bα-Octahydro-1,1,7β,7Aβ-Tetramethyl-2H-Cyclopropa[A]Naphthalen-2-One
CAS No.	27779-52-8
Molecular Formula	C15H24O
Molecular Weight	220.35 g/mol
Synonyms	Ambrox; Ambroxan; Ambroxide; (1As)-1,1Aα,4,5,6,7,7A,7Bα-Octahydro-1,1,7β,7Aβ-Tetramethyl-2H-Cyclopropa[A]Naphthalen-2-One; (-)-Ambrox; (3aR,5aS,9aS,9bR)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan; 2H-Cyclopropa[a]naphthalen-2-one, 1,1a,4,5,6,7,7a,7b-octahydro-1,1,7b,7a-tetramethyl-, (1aS,7aS,7bS)-; 1,1a,4,5,6,7,7a,7b-Octahydro-1,1,7b,7a-tetramethyl-2H-cyclopropa[a]naphthalen-2-one
EINECS	Contact for details

Quality Control

Our (1As)-1,1Aα,4,5,6,7,7A,7Bα-Octahydro-1,1,7β,7Aβ-Tetramethyl-2H-Cyclopropa[A]Naphthalen-2-One is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, impurities, and physical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (GC/HPLC)	≥ 98.0%
Melting Point	75°C - 82°C
Optical Rotation [α]20/D	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.