Description

2-(3-Trifluoromethylbenzoyl)Pyridine is a high-purity fluorinated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique reactivity imparted by the trifluoromethylbenzoyl group, enabling precise molecular construction for high-value applications. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and light-emitting components, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(3-Trifluoromethylbenzoyl)Pyridine
CAS No.	27693-47-6
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	2-(3-(Trifluoromethyl)benzoyl)pyridine; 3'-Trifluoromethyl-2-pyridyl phenyl ketone; 2-Pyridyl 3-trifluoromethylphenyl ketone; (3-Trifluoromethylphenyl)(pyridin-2-yl)methanone; 2-(α,α,α-Trifluoro-m-toluoyl)pyridine; m-Trifluoromethyl-2-benzoylpyridine; 27693-47-6
EINECS	Contact for details

Quality Control

Our 2-(3-Trifluoromethylbenzoyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.